Publications
The Effects of Pregnancy on Disease Progression of Retinitis Pigmentosa
Malena Daich Varela, Memuna Rashid, Andre Lopes, and Michel Michaelides
American Journal of Ophthalmology, 2025
Nivolumab and Ipilimumab for Metastatic Castration-Resistant Prostate Cancer With an Immunogenic Signature: The Multicenter, Two-Cohort, Phase II NEPTUNES Study
Gianmarco Leone, Yien Ning Sophia Wong, Robert J. Jones, Peter Sankey, Debra H. Josephs, Simon J. Crabb, Louise Harris, Anjali Zarkar, Andrew Protheroe, Naveen Vasudev, Memuna Rashid, Andre Lopes, Aniqa Tasnim, Leah Ensell, John Hartley, Anuradha Jayaram, Bihani Kularatne, Mahaz Kayani, Colin C. Pritchard, Eric Q. Konnick, Alex Freeman, Aiman Haider, Josep Linares, Gerhardt Attard, Sergio A. Quezada, Charles Swanton, Teresa Marafioti, and Mark D. Linch
Journal of Clinical Oncology, 2025
Molecular targeted maintenance therapy versus standard of care in advanced biliary cancer: an international, randomised, controlled, open-label, phase III umbrella trial (SAFIR-ABC10-Precision Medicine)
D. Malka, I. Borbath, A. Lopes, D. Couch, M. Jimenez, T. Vandamme, J.W. Valle, J. Wason, E. Ambrose, L. Dewever, I. De Bruyne, J. Edeline, J. Bridgewater
ESMO Open, 2025
Which adiposity index is best? Comparison of five indicators and their ability to identify type 2 diabetes risk in a population study
Cunrong Huang, Andre Lopes, Annie Britton
Diabetes Research and Clinical Practice, 2025
Reply to letter comments on: Molecular targeted maintenance therapy versus standard of care in advanced biliary cancer: an international, randomised, controlled, open-label, phase III umbrella trial (SAFIR-ABC10-Precision Medicine)
D. Malka, I. Borbath, A. Lopes, T. Vandamme, J. Edeline, J. Bridgewater
ESMO Open, 2025
Association of candidate surrogate endpoints with overall survival in advanced biliary tract cancer
Florian Castet, Carles Fabregat-Franco, John Bridgewater, Jin Won Kim, Margherita Rimini, Adelaida La Casta, Angela Lamarca, Minsu Kang, Francesca Salani, Alfredo Castillo, Andre Lopes, Jaewon Hyung, Lorenza Rimassa, Jorge Adeva, Daniel López-Valbuena, Míriam Basagaña-Farres, Simran Vaja, Ka Man Mak, Tian V. Tian, Andrés Muñoz, Enrique Aranda, Míriam Lobo, Paloma Peinado, Javier Sastre, Ana Fernández-Montes, Begoña Graña, Eva Martínez de Castro, Javier Gallego, Ruth Vera, Inmaculada Alés, Inmaculada Gallego, Teresa García García, Berta Laquente, David Páez, Mercedes Rodríguez-Garrote, Marcos Melián, Roberto Pazo-Cid, Mónica Guillot, David Gutiérrez, Ignacio García Escobar, Teresa Macarulla, Andrea Casadei-Gardini, Lorenzo Fornaro, Mario Domenico Rizzato, Lorenzo Antonuzzo, Federico Rossari, Tomoyuki Satake, Hanne Vandeputte, Caterina Vivaldi, Tiziana Pressiani, Jessica Lucchetti, Oluseyi Abidoye, Ilario Giovanni Rapposelli, Stefano Tamberi, Fabian Finkelmeier, Guido Giordano, Federico Nichetti, Hong Jae Chon, Chiara Braconi, Emiliano Tamburini, Alessandro Parisi, Anna Diana, Mario Scartozzi, Gerald W. Prager, Marta Schirripa, Il Hwan Kim, Lukas Perkhofer, Ester Oneda, Monica Verrico, Stephen L. Chan, Ingrid Garajova, Maria Grazia Rodriquenz, Silvana Leo, Antonio De Rosa, Daniele Lavacchi, Silvia Foti, Masafumi Ikeda, Jeroen Dekervel, Monica Niger, Giuseppe Tonini, Tanios Bekaii-Saab, Luca Esposito, Alessandra Boccaccino, Selma Ahcene Djaballah, Valentina Zanuso, Gianluca Masi, Sara Lonardi, Changhoon Yoo, Juan W. Valle, Teresa Macarulla
Journal of Hepatology, 2025
CD19/CD22 targeting with cotransduced CAR T cells to prevent antigen-negative relapse after CAR T-cell therapy for B-cell ALL
Sara Ghorashian, Giovanna Lucchini, Rachel Richardson, Kyvi Nguyen, Craig Terris, Aleks Guvenel, Macarena Oporto-Espuelas, Jenny Yeung, Danielle Pinner, Jan Chu, Lindsey Williams, Ka-Yuk Ko, Chloe Walding, Kelly Watts, Sarah Inglott, Rebecca Thomas, Christopher Connor, Stuart Adams, Emma Gravett, Kimberly Gilmour, Alka Lal, Sangeetha Kunaseelan, Bilyana Popova, Andre Lopes, Yenting Ngai, Allan Hackshaw, Evangelia Kokalaki, Milena Balascha Carulla, Khushnuma Mullanfiroze, Arina Lazareva, Vesna Pavasovic, Anupama Rao, Jack Bartram, Ajay Vora, Robert Chiesa, Juliana Silva, Kanchan Rao, Denise Bonney, Robert Wynn, Martin Pule, Rachael Hough, Persis J. Amrolia
Blood, 2024
The IMRiS Trial: A Phase 2 Study of Intensity Modulated Radiation Therapy in Extremity Soft Tissue Sarcoma
Beatrice Seddon, Franel Le Grange, Rita Simões, Chris Stacey, Shumona Shelly, Sharon Forsyth, Laura White, Charles Candish, Peter Dickinson, Aisha Miah, Syed Ali Moinuddin, James Wylie, Andre Lopes
International Journal of Radiation Oncology, Biology, Physics, 2024
Quality-of-life outcomes in metastatic spinal cord compression: findings from the SCORAD trial
Peter J. Hoskin, Krystyna Reczko, Memuna Rashid, Allan Hackshaw, Andre Lopes
JNCI: Journal of the National Cancer Institute, 2024
Aetiology of liver disease and response to immune checkpoint inhibitors: An updated meta-analysis confirms benefit in those with non-viral liver disease
Tim Meyer, Sevasti Galani, Andre Lopes, Arndt Vogel
European Association for the Study of the Liver, 2023
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
Nathaniel D. Anderson, Jack Birch, Theo Accogli, Ignacio Criado, Eleonora Khabirova, Conor Parks, Yvette Wood, Matthew D. Young, Tarryn Porter, Rachel Richardson, Sarah J. Albon, Bilyana Popova, Andre Lopes, Robert Wynn, Rachael Hough, Satyen H. Gohil, Martin Pule, Persis J. Amrolia, Sam Behjati, Sara Ghorashian
Nature Medicine, 2023
Immunotherapy with CD25/CD71-allodepleted T cells to improve T-cell reconstitution after matched unrelated donor hematopoietic stem cell transplant: a randomized trial
Karl S. Peggs, Sarah J. Albon, Macarena Oporto Espuelas, Catherine Irving, Rachel Richardson, Joan Casanovas-Company, Rebecca Wallace, Aleks Guvenel, Sara Ghorashian, Angela Collura, Meera Subramaniyam, Barry Flutter, Bilyana Popova, Fernanda Castro, Andre Lopes, Kim Champion, Oliver Schofield, Laura Clifton-Hadley, Thomas Taylor, Maria Farrell, Stuart Adams, Kimberly C. Gilmour, Stephen Mackinnon, Eleni Tholouli, Persis J. Amrolia
Cytotherapy, 2022
PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer
David J. Propper, Fangfei Gao, Mark P. Saunders, Debashis Sarker, John A. Hartley, Victoria J. Spanswick, Helen L. Lowe, Louise D. Hackett, Tony T. Ng, Paul R. Barber, Gregory E. Weitsman, Sarah Pearce, Laura White, Andre Lopes, Sharon Forsyth, Daniel Hochhauser
British Journal of Cancer, 2022
Prognostic factors for survival and ambulatory status at 8 weeks with metastatic spinal cord compression in the SCORAD randomised trial
Peter J. Hoskin, Kirsten Hopkins, Vivek Misra, Tanya Holt, Rhona McMenemin, Fiona McKinna, Krishnaswamy Madhavan, Andrew Bates, Noelle O'Rourke, Jason F. Lester, Tim Sevitt, Daniel Roos, Gillian Brown, Sharon Shibu Thomas, Sharon Forsyth, Krystyna Reczko, Allan Hackshaw, Catherine O'Hara, Andre Lopes
Radiotherapy and Oncology, 2022
Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation
Rachael Hough, Andre Lopes, Pip Patrick, Nigel Russell, Kavita Raj, Eleni Tholouli, John A. Snowden, Matthew Collin, Nadjet El-Mehidi, Anthony Lawrie, Laura Clifton-Hadley, Paul Veys, Charles Craddock, Stephen Mackinnon, Gordon Cook, Bronwen Shaw, David Marks
Blood Advances, 2022
Visualising harms in publications of randomised controlled trials: consensus and recommendations
Rachel Phillips, Suzie Cro, Graham Wheeler, Simon Bond, Tim P Morris, Siobhan Creanor, Catherine Hewitt, Sharon Love, Andre Lopes, Iryna Schlackow, Carrol Gamble, Graeme MacLennan, Chris Habron, Anthony C Gordon, Nikhil Vergis, Tianjing Li, Riaz Qureshi, Colin C Everett, Jane Holmes, Amanda Kirkham, Clare Peckitt, Sarah Pirrie, Norin Ahmed, Laura Collett, Victoria Cornelius
BMJ, 2022
Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients
Luca Biasco, Natalia Izotova, Christine Rivat, Sara Ghorashian, Rachel Richardson, Aleks Guvenel, Rachael Hough, Robert Wynn, Bilyana Popova, Andre Lopes, Martin Pule, Adrian J. Thrasher, Persis J. Amrolia
Nature Cancer, 2021
Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis
Claire Petit, Benjamin Lacas, Jean-Pierre Pignon, Quynh Thu Le, Vincent Grégoire, Cai Grau, Allan Hackshaw, Björn Zackrisson, Mahesh K B Parmar, Ju-Whei Lee, Maria Grazia Ghi, Giuseppe Sanguineti, Stéphane Temam, Maurice Cheugoua-Zanetsie, Brian O'Sullivan, Marshall R Posner, Everett E Vokes, Juan J Cruz Hernandez, Zbigniew Szutkowski, Eric Lartigau, Volker Budach, Rafal Suwiński, Michael Poulsen, Shaleen Kumar, Sarbani Ghosh Laskar, Jean-Jacques Mazeron, Branislav Jeremic, John Simes, Lai-Ping Zhong, Jens Overgaard, Catherine Fortpied, Pedro Torres-Saavedra, Jean Bourhis, Anne Aupérin, Pierre Blanchard
Lancet Oncol, 2021
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group
Benjamin Lacas, Alexandra Carmel, Cécile Landais, Stuart J. Wong, Lisa Licitra, Jeffrey S. Tobias, Barbara Burtness, Maria Grazia Ghi, Ezra E.W. Cohen, Cai Grau, Gregory Wolf, Ricardo Hitt, Renzo Corvò, Volker Budach, Shaleen Kumar, Sarbani Ghosh Laskar, Jean-Jacques Mazeron, Lai-Ping Zhong, Werner Dobrowski, Pirus Ghadjar, Carlo Fallai, Branko Zakotnik, Atul Sharma, René-Jean Bensadoun, Maria Grazia Ruo Redda, Séverine Racadot, George Fountzilas, David Brizel, Paolo Rovea, Athanassios Argiris, Zoltán Takácsi-Nagy, Ju-Whei Lee, Catherine Fortpied, Jonathan Harris, Jean Bourhis, Anne Aupérin, Pierre Blanchard, Jean-Pierre Pignon
Radiotherapy and Oncology, 2021
Impact of compliance to chemoradiation on long-term outcomes in squamous cell carcinoma of the anus: results of a post hoc analysis from the randomised phase III ACT II trial
R. Glynne-Jones, H.M. Meadows, A. Lopes, R. Muirhead, D. Sebag-Montefiore, R. Adams
Annals of Oncology, 2020
Histographic analysis of oedema and fat in inflamed bone marrow based on quantitative MRI
Timothy J. P. Bray, Naomi Sakai, Alexandra Dudek, Corinne Fisher, Kannan Rajesparan, Andre Lopes, Coziana Ciurtin, Debajit Sen, et al.
European Radiology, 2020
Landmark survival analysis and impact of anatomic site of origin in prospective clinical trials of biliary tract cancer
Mairéad Geraldine McNamara, Andre Lopes, Harpreet Wasan, Tanios Bekaii-Saab, John Bridgewater, Juan W. Valle
Journal of Hepatology, 2020
Prognostic Threshold for Circulating Tumor Cells in Patients With Pancreatic and Midgut Neuroendocrine Tumors
Dalvinder Mandair, Mohid S. Khan, Andre Lopes, Luke Furtado O'Mahony, Leah Ensell, Helen Lowe, John A. Hartley, Christos Toumpanakis, Martyn Caplin, Tim Meyer
The Journal of Clinical Endocrinology & Metabolism, 2020
A Phase I/ II Feasibility Study of Intravenous Cetuximab in Combination with 5 days Weekly Oral Capecitabine and Preoperative Radiotherapy in Rectal Cancer (XERXES)
Robert Glynne-Jones, Helen M Meadows, Andre Lopes, Pippa Riddle, Marian Duggan, David Sebag-Montefiore, Alec McDonald, Les Samuel, Stephen Falk, Richard Adams
Archives of Clinical and Biomedical Research, 2020
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR
Sara Ghorashian, Anne Marijn Kramer, Shimobi Onuoha, Gary Wright, Jack Bartram, Rachel Richardson, Sarah J. Albon, Joan Casanovas-Company, Fernanda Castro, Bilyana Popova, Krystle Villanueva, Jenny Yeung, Winston Vetharoy, Aleks Guvenel, Patrycja A. Wawrzyniecka, Leila Mekkaoui, Gordon Weng-Kit Cheung, Danielle Pinner, Jan Chu, Giovanna Lucchini, Juliana Silva, Oana Ciocarlie, Arina Lazareva, Sarah Inglott, Kimberly C. Gilmour, Gulrukh Ahsan, Mathieu Ferrari, Somayya Manzoor, Kim Champion, Tony Brooks, Andre Lopes, Allan Hackshaw, Farzin Farzaneh, Robert Chiesa, Kanchan Rao, Denise Bonney, Sujith Samarasinghe, Nicholas Goulden, Ajay Vora, Paul Veys, Rachael Hough, Robert Wynn, Martin A. Pule, Persis J. Amrolia
Nature Medicine, 2019
Sacroiliac Joint Ankylosis in Young Spondyloarthritis Patients Receiving Biologic Therapy: Observation of Serial Magnetic Resonance Imaging Scans
Timothy J. P. Bray, Andre Lopes, Corinne Fisher, Coziana Ciurtin, Debajit Sen, Margaret A. Hall-Craggs
Arthritis & Rheumatology, 2019
Effect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial
Peter J. Hoskin, Kirsten Hopkins, Vivek Misra, Tanya Holt, Rhona McMenemin, Danny Dubois, Fiona McKinna, Bernadette Foran, Krishnaswamy Madhavan, Carol MacGregor, Andrew Bates, Noelle O'Rourke, Jason F. Lester, Tim Sevitt, Daniel Roos, Sanjay Dixit, Gillian Brown, Seonaid Arnott, Sharon Shibu Thomas, Sharon Forsyth, Sandy Beare, Krystyna Reczko, Allan Hackshaw, Andre Lopes
JAMA, 2019
Treatment of classical Hodgkin lymphoma in young adults aged 18-30 years with a modified paediatric Hodgkin lymphoma protocol. Results of a multicentre phase II clinical trial (CRUK/08/012)
William Townsend, Sarah Leong, Peter Hoskin, Patricia Diez, Pip Patrick, David Linch, Wai-Lup Wong, Irfan Kayani, Bal Sanghera, Andre Lopes, Stephen Daw, Graham Collins, Laura Clifton-Hadley, Kirit Ardeshna
British Journal of Haematology, 2019
Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial
Alison C. Backen, Andre Lopes, Harpreet Wasan, Daniel H Palmer, Marian Duggan, David Cunningham, Alan Anthoney, Pippa G. Corrie, Srinivasan Madhusudan, Anthony Maraveyas, Paul J. Ross, Justin S. Waters, William P. Steward, Charlotte Rees, Mairéad G. McNamara, Sandy Beare, John A. Bridgewater, Caroline Dive, Juan W. Valle
British Journal of Cancer, 2018
Advanced Intrahepatic Cholangiocarcinoma: Post Hoc Analysis of the ABC-01, -02, and -03 Clinical Trials
Angela Lamarca, Paul Ross, Harpreet S. Wasan, Richard A. Hubner, Mairéad G. McNamara, Andre Lopes, Prakash Manoharan, Daniel Palmer, John Bridgewater, Juan W. Valle
JNCI Journal of the National Cancer Institute, 2018
BACCHUS: A randomised non-comparative phase II study of neoadjuvant chemotherapy (NACT) in patients with locally advanced rectal cancer (LARC)
R. Glynne-Jones, M.R. Hall, A. Lopes, S. Pearce, V. Goh, S. Bosompem, J. Bridgewater, I. Chau, H. Wasan, B. Moran, L. Melcher, N.P. West, P. Quirke, W.-L. Wong, S. Beare, N. Hava, M. Duggan, M. Harrison
Heliyon, 2018
High-dose chemotherapy and autologous stem cell transplantation in enteropathy-associated and other aggressive T-cell lymphomas: a UK NCRI/Cancer Research UK Phase II Study
Elizabeth H. Phillips, Michelle M. Lannon, Andre Lopes, Humra Chadwick, Gail Jones, Michal Sieniawski, Andrew Davies, Katrina Wood, Laura Clifton-Hadley, Paul Smith, Anthony Lawrie, Nick Chadwick, Anne L. Lennard
Bone Marrow Transplantation, 2018
Whole-body MRI for staging and interim response monitoring in paediatric and adolescent Hodgkin's lymphoma: a comparison with multi-modality reference standard including 18F-FDG-PET-CT
Arash Latifoltojar, Shonit Punwani, Andre Lopes, Paul D. Humphries, Maria Klusmann, Leon Jonathan Menezes, Stephen Daw, Ananth Shankar, Deena Neriman, Heather Fitzke, Laura Clifton-Hadley, Paul Smith, Stuart A. Taylor
European Radiology, 2018
Clinical endpoints in trials of chemoradiation for patients with anal cancer
Robert Glynne-Jones, Richard Adams, Andre Lopes, Helen Meadows
Lancet Oncol, 2017
Diagnostic utility of whole body Dixon MRI in multiple myeloma: A multi-reader study
Timothy J.P. Bray, Saurabh Singh, Arash Latifoltojar, Kannan Rajesparan, Farzana Rahman, Priya Narayanan, Sahar Naaseri, Andre Lopes, Alan Bainbridge, Shonit Punwani, Margaret A. Hall-Craggs
PLoS ONE, 2017
Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations
Simon Gollins, Nick West, David Sebag-Montefiore, Arthur Sun Myint, Mark Saunders, Shabbir Susnerwala, Phil Quirke, Sharadah Essapen, Leslie Samuel, Bruce Sizer, Jane Worlding, Katie Southward, Gemma Hemmings, Emma Tinkler-Hundal, Morag Taylor, Daniel Bottomley, Philip Chambers, Emma Lawrie, Andre Lopes, Sandy Beare
British Journal of Cancer, 2017
Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials
Mairéad Geraldine McNamara, John Bridgewater, Andre Lopes, Harpreet Wasan, David Malka, Lars Henrik Jensen, Takuji Okusaka, Jennifer J. Knox, Dorothea Wagner, David Cunningham, Jenny Shannon, David Goldstein, Markus Moehler, Tanios Bekaii-Saab, Juan W. Valle
BMC Cancer, 2017
Prognostic factors for progression-free and overall survival in advanced biliary tract cancer
J.Bridgewater, A.Lopes, H.Wasan, D.Malka, L.Jensen, T.Okusaka, J.Knox, D.Wagner, D.Cunningham, J.Shannon, D.Goldstein, M.Moehler, T.Bekaii-Saab, M.G.McNamara, J.W.Valle
Annals of Oncology, 2016
A phase 1b study of Selumetinib in combination with Cisplatin and Gemcitabine in advanced or metastatic biliary tract cancer: the ABC-04 study
John Bridgewater, Andre Lopes, Sandra Beare, Marian Duggan, Dymphna Lee, Maravic Ricamara, Delyth McEntee, Ajithkumar Sukumaran, Harpreet Wasan, Juan W. Valle
BMC Cancer, 2016
Quality of life, long-term survivors and long-term outcome from the ABC-02 study
John Bridgewater, Andre Lopes, Daniel Palmer, David Cunningham, Alan Anthoney, Anthony Maraveyas, Srinivasan Madhusudan, Tim Iveson, Juan Valle, Harpreet Wasan
British Journal of Cancer, 2016
Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial
Juan W Valle, Harpreet Wasan, Andre Lopes, Alison C Backen, Daniel H Palmer, Karen Morris, Marian Duggan, David Cunningham, D Alan Anthoney, Pippa Corrie, Srinivasan Madhusudan, Anthony Maraveyas, Paul J Ross, Justin S Waters, Will P Steward, Charlotte Rees, Sandy Beare, Caroline Dive, John A Bridgewater
Lancet Oncol, 2015